Know the Signs, Fight for Victory

Meeting Overview 

Science in Paris stands in the proud tradition of The Marfan Foundation’s prior meetings with national and international researchers and clinicians focused on genetic aortic and vascular conditions. The goal is to enhance collaboration and discovery to ultimately benefit patients and families. This four-day meeting will feature three separate, but connected meetings. Clinicians (in all disciplines), surgeons, and researchers are all invited to attend. Oral presentations and social events, including a dinner cruise along the Seine, are planned. Poster sessions are scheduled for August 29, August 31, and September 1.

The three meetings are: 

August 29, 2022
– DEFY Foundation 5th Scientific Meeting on Vascular Ehlers-Danlos Syndrome
August 30-31, 2022 
– 11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions
September 1, 2022
– 7th GenTAC Aortic Summit 

Thank you to our sponsors

Meeting Details

  • DEFY Foundation 5th Scientific Meeting on Vascular Ehlers-Danlos Syndrome 

    The DEFY Foundation, in partnership with The Marfan Foundation and The VEDS Movement, invites you to participate in the 5th Scientific Meeting on Vascular Ehlers-Danlos syndrome (VEDS).

    The goal of this meeting is to bring together the international VEDS research and treatment communities to enable interaction and networking. Scientists and clinicians will be able to focus on state-of-the-art research using mouse models, natural history experience, critical patient outcomes, and management issues and start collaborations in order to help encourage participation in upcoming clinical trials. The meeting will have three to five general session topics driven by abstract submissions, where young investigators present their state-of-the-art science. A poster session will follow the general session to allow interaction and networking.

    All presentations (in both oral and poster formats) will be selected from the abstracts. Abstracts are welcome in all disciplines aimed at identifying or testing medical or surgical interventions, unveiling molecular mechanisms, insights derived from animal models, innovative technologies, provocative concepts, mutation-specific patient-reported natural history, and surgical outcomes for both children and adults.

    In collaboration with:

     

  • 11th International Research Symposium on Marfan, Loeys-Dietz, and Related Conditions 

    The 11th International Research Symposium on Marfan, Loeys-Dietz (LDS), and Related Conditions is a two-day state-of-the-art meeting where new cutting-edge research in diagnosis, treatment, and pathogenesis of Marfan, LDS, and related conditions will be presented and discussed. The goal is to bring together young and senior investigators in both clinical and basic research to investigate mechanisms by which mutations are translated to phenotype, recognition of the broad clinical range of aneurysm-related syndromes, and identification of genes that harbor mutations, and investigate effective therapies. All research and management issues in major disciplines – including cardiology, surgery, orthopedics, genetics, and ophthalmology – are encouraged. Young investigators are encouraged to submit their research for review, and state-of-the-art science will be selected for oral presentation through abstract submission. A poster session will follow the general session to allow interaction and networking.

    All presentations (in both oral and poster formats) will be selected from the abstracts. Submissions are welcomed in state-of-the-art research and management in cardiology, pulmonology, ophthalmology, and orthopedic issues; new imaging and biomarkers, genotype/ phenotype/modifiers, groundbreaking technologies, challenging concepts, and development of therapeutic options, animal models, and pathogenesis; pregnancy; exercise; and quality of life.

  • 7th GenTAC Aortic Summit 

    The agenda for the GenTAC Aortic Summit focuses on clinical science in the field of genetically triggered thoracic aortic aneurysms. The goal of the Aortic Summit is to recognize the similarities and differences, as well as the critical management and surgical issues facing patients with thoracic aortic disease.

    Key sessions include presentations on the following topics from experts in the field:

    Familial Aortopathy

      • The Current Genetic Library & Likely Prospects
      • Gene-specific Decision-making Using Imaging
      • Gene-specific Decision-making Using Surgical Cut Points
      • Gene-specific Management in Pregnancy

    Bicuspid Aortic Valve (BAV)

      • The Search for Genetic Underpinnings
      • Phenotypic Variations – The Valve
      • Phenotypic Variations – The Aorta
      • Pediatric Controversies, including Exercise and Sports
      • Debate: Should the surgical cut point for BAV be the same or different from non-genetic aortopathies?

    Turner Syndrome

      • Advances in Genetic Understanding
      • Pearls in Managing Patients

    Acute Aortic Syndrome

      • Current Classification Schemes
      • Debate: Should we operate on ascending intramural hematoma?
      • Debate: Should we stent stable Type B?
      • How to Use Biomarkers Acutely & Chronically

    Abstract submissions addressing the similarities and differences and the critical management and surgical issues facing patients with thoracic aortic disease, the natural history of disease, and patient outcomes are welcome.

Important Dates & Deadlines 

May 16, 2022 Abstract Submission Deadline 
June 17, 2022 Abstract Presentation Notification 
August 1, 2022 Early Registration Deadline 
August 1, 2022 Hotel Reservation Deadline 

Fees & Registration 

  • Early Registration 

    $499 USD when you register April 15 – August 1, 2022 for the full conference (4 days).

  • Single Day Early Registration 

    $200 USD when you register April 15 – August 1, 2022 for a single conference day.

  • Late Registration 

    $650 USD when you register August 2 – August 29, 2022 for the full conference (4 days).

  • Single Day Late Registration 

    $300 USD when you register August 2 – September 1, 2022 for a single conference day.

  • Students, Fellows, Postdocs & VHO Leaders

    $350 USD when you register April 15 – August 1, 2022 as a student, fellow, postdoc, or volunteer health organization (VHO) leader for the full conference (4 days).

  • Seine River Cocktails and Canapés Boat Cruise

    $150 USD

    This event is scheduled for August 30, 2022, from 6:00 – 10:00 p.m.

    For more information click here.

Hotel & Travel 

Science in Paris will take place at: 

Le Méridien Etoile, Paris, France 

81 Boulevard Gouvion Saint-Cyr 

75848 Cedex 17 

Paris 75017 France 

+33 1 40 68 34 34 

Ideally situated in the heart of Paris and facing the Palais des Congrès de Paris, the hotel is located near the La Défense business district and within walking distance of the Arc de Triomphe and Champs-Elysées. It is also near the Louvre Museum, Eiffel Tower, and Montmartre – all of which make Paris one of the most beautiful cities in the world.  

Charles de Gaulle and Orly Airports are only 30-45 minutes from the hotel. The Le Bus Direct shuttle to Charles de Gaulle stops across the street every 30 minutes. The famed Gare du Nord train station is a mere 20 minutes away for those traveling to or from other cities aboard the Eurostar.  

The cost of accommodations is 219€ for single occupancy and 239€ for double occupancy and includes breakfast. Hotel reservations must be made by August 1, 2022, to guarantee the group rate and availability.  

Rates will be made available for three days pre-event and three days post-event. Individual reservations can be canceled up to 21 days before arrival. Deposits for room reservations are required at booking – one night for any stay of one night or two nights; three nights for any stay of three nights or more.  

Abstract Submission 

Please use the following guidelines when submitting abstracts to be reviewed for Science in Paris:  

  • Abstracts must be submitted electronically by May 16, 2022.  
  • Abstracts must be written in English.  
  • The names and details of the authors should be listed in the following order: Last name, first name, degree, department, institution, city, state, and country.  
  • The presenting author’s name should be underlined.  
  • The abstract should be a maximum of 300 words and include the following sections: introduction, objectives, materials and methods, results, and conclusion.  
  • Please use 12 pt. Arial, single-spaced, and 1” margins.  
  • Abstracts must be only one page and have no diagrams.  
  • There is no limit to the number of abstracts a presenter can submit.  
  • All authors will receive notification by June 17 for oral or poster presentations. 

Details on the kinds of abstracts requested for each meeting are outlined below.  

  • DEFY Foundation 5th Scientific Meeting on Vascular Ehlers-Danlos Syndrome 

    All presentations (in both oral and poster formats) will be selected from the abstracts. Abstracts are welcome in all disciplines aimed at identifying or testing medical or surgical interventions, unveiling molecular mechanisms, insights derived from animal models, innovative technologies, provocative concepts, mutation-specific patient-reported natural history, and surgical outcomes for both children and adults.

  • 11th International Research Symposium on Marfan, Loeys-Dietz, and Related Conditions 

    All presentations (in both oral and poster formats) will be selected from the abstracts. Submissions in state-of-the-art research and management in cardiology, pulmonology, ophthalmology, and orthopedic issues; new imaging and biomarkers, genotype/ phenotype/modifiers, groundbreaking technologies, challenging concepts, and development of therapeutic options, animal models, and pathogenesis; pregnancy; exercise; and quality of life are welcome.

  • 7th GenTAC Aortic Summit 

    Abstract submissions addressing the similarities and differences and the critical management and surgical issues facing patients with thoracic aortic disease, the natural history of disease, and patient outcomes are welcome.